Pluto Bioinformatics

GSE95822: Length-independent telomere damage drives cardiomyocyte senescence

Bulk RNA sequencing

Ageing is the biggest risk factor to cardiovascular health and is associated with increased incidence of cardiovascular disease. Cellular senescence, a process driven in part by telomere shortening has been implicated in age-related cardiac dysfunction. However, the role of cellular senescence and its underlying mechanisms in slowly dividing/post-mitotic cardiomyocytes is not understood. SOURCE: Neil,Alistair,Robertson (neil.alistair.robertson@hotmail.co.uk) - P. Adams University of Glasgow

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