Pluto Bioinformatics

GSE150392: RNA-Seq of Human iPSC-cardiomyocytes infected with SARS-CoV-2

Bulk RNA sequencing

Coronavirus disease 2019 (COVID-19) is a viral pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is predominantly defined by respiratory symptoms, but cardiac complications including arrhythmias, heart failure, and viral myocarditis are also prevalent. Although the systemic ischemic and inflammatory responses caused by COVID-19 can detrimentally affect cardiac function, the direct impact of SARS-CoV-2 infection on human cardiomyocytes is not well understood. SOURCE: yizhou wang (yizhou.wang@cshs.org) - cedars sinai medical center