Pluto Bioinformatics

GSE150220: Effects of Pten knockout in dystrophic skeletal muscles of mdx mouse

Bulk RNA sequencing

Analysis of skeletal muscles with specific knockout (KO) of Phosphatase and tensin homolog (Pten) gene in an animal model of DMD (mdx mice). Pten knockout alleviates myofiber degeneration and restores muscle function in mdx mice. SOURCE: Shihuan Kuang (skuang@purdue.edu) - Purdue University