Pluto Bioinformatics

GSE140357: Transcriptome anaylisis of WT and GFAT-1 G451E engineered N2a cells by RNA-Seq

Bulk RNA sequencing

Transcriptome of N2a cells carrying a GFAT-1 gain-of-function point mutation that results in a G451E amino acid substitution were compared to WT N2a transcriptome profiles. Three replicates of both cell lines were analyzed. Additionally WT N2a cells were treated with 10 mM GlcNAc for 24h prior to transcriptome analysis resulting in a third dataset with 3 replicates. SOURCE: Martin Denzel (mdenzel@age.mpg.de) - Max Planck Institute for Biology of Ageing