Pluto Bioinformatics

GSE86609: The Arcuate Estrogenome: Estrogen Response Element-dependent and -independent Signaling of ER

Bulk RNA sequencing

We used three genotypes of mice: 1) wild-type, 2) KIKO (knock in/knock out), which lack a functional ERE-binding domain, and 3) ERKO (total ER knockout) to determine ERE-dependent and -independent signaling of E2 in the arcuate nucleus of mice. SOURCE: Troy,A.,Roepke (ta.roepke@rutgers.edu) - Rutgers University