Pluto Bioinformatics

GSE144503: -Catenin and FGFR2 Regulate Postnatal Rosette-Based Adrenocortical Morphogenesis

Bulk RNA sequencing

We show that -catenin stabilization leads to increased FGFR2, which is required for rosette formation by regulating AJ stability and dynamics. Our results provide the basis for studying adrenal glomerular morphogenesis and the role of rosettes in on-going zG tissue maintenance and function. SOURCE: David Breault (david.breault@childrens.harvard.edu) - Breault Lab Boston Childrens Hospital