Pluto Bioinformatics

GSE130822: Ascl2-dependent cell differentiation drives regeneration of abated intestinal stem cells

Bulk RNA sequencing

Functions of Ascl2 in colonic stem cell maintenance and regeneration. We used RNA-sequencing to profile gene expression in regenerating crypt cells and Ascl2-deficient colonic stem cells, and ASCL2 ChIP-seq to identify transcriptional target genes.; SOURCE: Ramesh Shivdasani (ramesh_shivdasani@dfci.harvard.edu) - Shivdasani Dana Farber Cancer Institute