Pluto Bioinformatics

GSE133211: PRC2 activates interferon-stimulated genes indirectly by repressing miRNAs in glioblastoma

Bulk RNA sequencing

Purpose: The goal of this study was to identify genes induced upon type I and II interferon response and how loss of PRC2/EZH2 impacts their induction.; Methods: mRNA-seq from cells treated with universal type I IFN alpha/beta or IFN gamma. miRNA-seq from GBM-derived tumor samples. SOURCE: Vishy Iyer (iyerlab@gmail.com) - University of Texas at Austin