Pluto Bioinformatics

GSE129315: Next Generation Sequencing identifies lymph node lymphatic endothelial cell genes regulated by RANKL

Bulk RNA sequencing

Purpose: The objective was to identify genes regulted by RANK signalling in lymph node lymphatic endothelial cells; Method: Lymphatic endothelial cells were FACS sorted from peripheral lymph nodes of mice deficient for stromal RANKL (Ccl19 Cre Rankl flox/flox) versus littermate controls (Rankl flox/flox) and processed for bulk RNA sequencing; Results: Upregulated and downregulated genes were identified SOURCE: Christopher,G.,Mueller (c.mueller@unistra.fr) - UPR3572 CNRS

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