Pluto Bioinformatics

GSE129186: RNA sequencing of WT and AICDA KO iPCS clones

Bulk RNA sequencing

We report AICDA facilitates nave pluripotency of mouse iPSCs by suppressing FGF/ERK signaling. In the absence of AICDA iPSCs fail to achive nave pluripotent state and display chracteristics of EpiSCs and are primed for differentiation. SOURCE: Ritu Kumar (rik2002@med.cornell.edu) - Weill Cornell Medicine