Pluto Bioinformatics

GSE80182: A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression

Bulk RNA sequencing

We sequenced mRNA from 3 biological replicates each of A549 lung adenocarcinoma cell lines expressing shRNA against GFP (control), PRMT5, or MEP50. We then determined differential gene expression. SOURCE: David Shechter (david.shechter@einstein.yu.edu) - Shechter Lab Albert Einstein College of Medicine