Pluto Bioinformatics

GSE84661: Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq]

Bulk RNA sequencing

Genome-wide chromosome conformation capture (Hi-C) and promoter-capture Hi-C (CHi-C) were performed during epidermal differentiation. These data indicate that dynamic and constitutive enhancer-promoter contacts combine to control gene induction during differentiation and that chromosome conformation enables discovery of new TFs with distinct roles in this process. SOURCE: Paul Khavari Stanford University