Pluto Bioinformatics

GSE136655: NON-CELL AUTONOMOUS FUNCTIONS OF SPHINGOSINE KINASE 2 AND TP53 IN ANTI-TUMOR IMMUNITY

Bulk RNA sequencing

We compared the global transcriptomes of wild type and SphK2 null fibroblasts by RNA-seq as a first step toward understanding the mechanism by which deletion or inhibition of SphK2 and elevation of p53 acts in a non-cell autonomous manner to create a hostile, anti-tumor microenvironment. SOURCE: Mikhail Dozmorov (mdozmorov@vcu.edu) - Virginia Commonwealth University