Pluto Bioinformatics

GSE126766: Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown

Bulk RNA sequencing

It is well known that insulin resistance in the obese state is associated with accumulation of neutral lipid in extra-adipose tissues. This phenomenon is particularly well-documented in skeletal muscle. The mechanistic underpinnings of this linkage are not fully understood. To define new MondoA target gene and pathway in human myotubes, we performed whole genome RNA sequencing. SOURCE: Byungyong Ahn (byahn@pennmedicine.upenn.edu) - University of Pennsylvania