Pluto Bioinformatics

GSE85491: RNA-SEQ analysis of the superficial, intermediate and basal cell layers of the bladder urothelium 24h after infection with UTI89 strain of E.coli and their adult female non-UTI controls.

Bulk RNA sequencing

Dissection and FACS cell sorting techniques were used to isolate the superficial, intermediate and basal cell types from the bladder urothelium of adult female mice following UTI infections, and their controls. This analysis will determine the transcriptional profile of each cell type, identify compartment specific transcripts, compartment specific transcript isoforms and cell-type specific noncoding RNAs. SOURCE: GUDMAP Developers (gudmap-editors@gudmap.org) - GUDMAP Database Group IGMM MRC Human Genetics Unit

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