Pluto Bioinformatics

GSE126618: Whsc1 controls mesendodermal transcription factor expression

Bulk RNA sequencing

We report here chromatin related factor Whsc1 links pluripotency exit and mesendodermal differentiation. We performed RNA-seqs to compare Whsc1+/+ and Whsc1-/- embryonic stem cells (ESCs) to compare the transcriptomes. UMI-4C experiments have been performed to identify regions having contacts with promoter regions of downstream Whsc1 targets: the mesendoderm transcritpion factors SOURCE: Maria Vila-Casadesús (maria.vila@crg.eu) - CRG

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