Pluto Bioinformatics

GSE125301: Inhibition of Phosphoinositide-3-kinase signaling promotes the stem cell state of trophoblast

Bulk RNA sequencing

We found that PI3K inhibition increased the expression of stem cell markers in trophoblast stem cells (TSCs). To better understand the PI3K inhibited cells, we compared untreated TSCs with cells treated with PI3K inhibitor ZSTK474 for 3h, 6h and 3 days. SOURCE: Cheryl Lee Duke-NUS Medical School