Pluto Bioinformatics

GSE74518: Adult-induced cardiac-specific knockout of Parkin provokes minimal transcriptional effect

Bulk RNA sequencing

Adult mice bearing homozygous floxed Parkin alleles (PMIDs 15249681, 21376232; TM Dawon), with or without the Myh6-driven MERCreMER transgene, were administered tamoxifen at 6-10 wks of age. Tissues were obtained from euthanized mice 9-10 weeks after tamoxifen induction. SOURCE: Scot,J,Matkovich (smatkovich@gmail.com) - Washington University School of Medicine