Pluto Bioinformatics

GSE93318: Genome-wide analysis of PER2 on BMAL1 DNA binding and transcription

Bulk RNA sequencing

We use PER2-inducible system to analyse BMAL1 chromatin binding by ChIPseq and expression profile by mRNA-Seq. PER2 decrease BMAL1 chromatin bindging but the effect on transcrtipion is gene-specific. SOURCE: Yi-Ying Chiou (YYCHIOU@EMAIL.UNC.EDU) - Aziz Sancar UNC_Chapel Hill