Pluto Bioinformatics

GSE100805: Decreased expression of a subset of TLR-dependent genes by heme-inducible Spi-C

Bulk RNA sequencing

To determine the functions of Spi-C in innate immune responses, we investigated the overall gene expression patterns in M-CSF-BMDMs prepared from Spicflox/flox and Lyz2-cre; Spicflox/flox mice. M-CSF-BMDMs were stimulated with or without LPS following heme treatment and used for RNA-seq analysis. SOURCE: Daisuke Okuzaki (dokuzaki@biken.osaka-u.ac.jp) - Research institute for microbial diseases, Osaka university