Pluto Bioinformatics

GSE105095: Human CXCR5+CD45RA-CD8+ T cells subset in follicular lymphoma

Bulk RNA sequencing

We demonstrate that CXCR5+CD8+ T cells are a distinct human T-cell subset that homes to follicles and exerts strong antitumor activity compared with CXCR5-CD8+ T cells. Importantly, this subset is associated with improved outcome in follicular lymphoma patients. SOURCE: Wencai Ma MD Anderson Cancer Center