Splenocytes were FACS-sorted from Wild-type and Mir146a-/- mice to isolate specific B-cell developmental stages. Utilizing high-throughput sequencing, we comparatively analyzed developmental stage-specific splenic B cell transcriptomes, including Transitional-1 (T1), Transitional-2 (T2), Marginal zone (MZ) and Follicular (FO) in both Wild-type and Mir146a-/- B cells. Two replicates of each developmental stage were submitted for high-throughput sequencing. SOURCE: matteo pellegrini (matteop@mcdb.ucla.edu) -  UCLA

Pluto Bioinformatics

GSE93252: RNA Sequencing Reveals Regulation of Marginal Zone B-Cell Differentiation by MicroRNA-146a