Pluto Bioinformatics

GSE130201: RNA-seq and ATAC-seq to study dendritic cell heterogeneity

Bulk RNA sequencing

The cDC2 subset is heterogeneous. We found the expression of T-bet delineates two distinct cDC2 subsets. Transcriptional profiling and analysis of chromatin accessibility in newly defined DC subsets identifies phenotypic specialisation and transcriptional regulators. SOURCE: Yuri Pritykin Memorial Sloan Kettering Cancer Center