Pluto Bioinformatics

GSE71340: Neoadjuvant chemotherapy modulates T cell responses in high-grade serous ovarian cancer metastases

Bulk RNA sequencing

Our data suggest that neoadjuvant chemotherapy enhances anti-cancer responses of T cells in peritoneal metastases of patients with high-grade serous ovarian cancer but does not decrease levels of immune checkpoint molecules, providing a rationale for sequential chemo-immunotherapy. SOURCE: Oliver Pearce (o.pearce@qmul.ac.uk) - Cancer and Inflammation Queen Mary University of London