Pluto Bioinformatics

GSE120858: MYCN knock-down leads to DNA-repair deficiency in human neuroblastoma (RNA-Seq)

Bulk RNA sequencing

We knock down MYCN in human neuroblastoma cell line by RNAi. MYCN knock-down caused global epigenome change, including nucleosome gain on key DNA-repair genes and promoter H3K9ac down regulation. SOURCE: Weisheng Zheng (wisense@2008.sina.com) - Jiang Lab Tongji University