Pluto Bioinformatics

GSE90136: Transcriptome analysis of Cdc73 deletion in AML cells

Bulk RNA sequencing

The Polymerase Associated Factor (PAFc) complex is an epigenetic regulating complex that has been shown to to be important for Acute Myeloid Leukemias harboring an MLL chromosomal translocations, such as MLL-AF9 leukemias. This study describes the transcriptomic profiling of AML cells following genetic deletion of the PAFc subunit Cdc73. SOURCE: Andrew Muntean (andrewmu@med.umich.edu) - Muntean University of Michigan