Pluto Bioinformatics

GSE65246: Expression profiling of E14 cells overexpressing Hk2/Pkm2

Bulk RNA sequencing

Purpose: In this study, we compared transcriptome profiling (RNA-seq) between normal mouse embryonic stem cell (E14) and Hexokinase2 (Hk2)/ Pyruvate Kinase M2 (Pkm2) overexpressed E14 cell.; Result: Using an optimized data analysis workflow, we mapped over 4 billion sequence reads per sample to the mouse genome (build mm9) and identified 28698 transcripts in 5 samples.; Conclusion: Our study represents the first detailed analysis of Hk2/ Pkm2 overexpressed E14 cell transcriptomes, generated by RNA-seq technology SOURCE: Hyunsoo Kim (khsoo82@snu.ac.kr) - Seoul National University

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