Pluto Bioinformatics

GSE149031 (human): Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in Multiple Myeloma

Bulk RNA sequencing

We have strong evidence on the essential role of Che-1 protein in promoting the proliferation of MM cells by sustaining chromatin dynamics and cellular transcription on a global scale using numerous experimental approaches, including a generation of a specific transgenic mouse model. SOURCE: Maurizio Fanciulli (maurizio.fanciulli@ifo.gov.it) - IRCCS National Institute of Cancer Regina Elena