Pluto Bioinformatics

GSE132883: B cell humoral response and differentiation is regulated by non-canonical poly(A) polymerase TENT5C.

Bulk RNA sequencing

Purpose: The goal of this study was to assess changes in the activated B cells transcriptome upon TENT5C knockout in mice; Methods: RNA-Seq data were obtained for LPS-activated primary B cells isolated from either wild-type or TENT5C KO mice; Results: Immunoglobulins transcripts were found to be downregulated in B cells isolated from TENT5C KO mice SOURCE: Pawel,S,Krawczyk (p.krawczyk@ibb.waw.pl) - Institute of Biochemistry and Biophysics PAS

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