Pluto Bioinformatics

GSE126230: HIV-1 SortSeq identifies HIV-1-infected cells from HIV-1-infected individuals

Bulk RNA sequencing

Using HIV-1 SortSeq, we identified HIV-1-infected cells containing inducible HIV-1 for RNAseq from resting CD4+ T cells treated with PMA/ionomycin for 16 hours from HIV-1-infected, antiretroviral therapy treated, virally suppressed individuals. Using custom bioinformatic pipeline, we identified HIV-1 genomic RNA, host RNA and HIV-1-host chimeric RNA junctions. SOURCE: Ya-Chi Ho (ya-chi.ho@yale.edu) - Yale University School of Medicine