A substantial population of intron retentions are stably maintained in poly-adenylated transcripts and a subset of them are excised upon neuronal stimulation. These regulated intron retention events in fully transcribed RNAs represent a mechanism to rapidly mobilize a pool of mRNAs in response to neuronal activity. SOURCE: oriane mauger (oriane.mauger@unibas.ch) -  Biozentrum of University of Basel

Pluto Bioinformatics

GSE89771: Targeted intron retention and excision for rapid gene regulation in response to neuronal activity