We used RNA-seq to profile the effect of a bacterially derived fatty on LPS-stimulated murine macrophages. From the transcriptional response, there was a significant decrease of inflammatory signals with lipid treatment, and pathway analysis of differentially expressed genes suggests PPAR alpha as potential anti-inflammatory mechanism. SOURCE: David Smith (dasm3869@colorado.edu) -  University of Colorado

Pluto Bioinformatics

GSE125930: Transcriptional profile of LPS-stimulated murine macrophages treated with bacterially derived fatty acid