Pluto Bioinformatics

GSE141525: The role of histone H3K27 acetylation for enhancer activity in embryonic stem cells

Bulk RNA sequencing

By substituting lysine 27 in histone variant H3.3 to arginine in mouse embryonic stem cells, we measured H3K27ac/H3K4me1/H3K4me3 and other acetylation modifications in H3.3K27R mutant cells, together with RNA-seq and ATAC-seq to measure the transcription activity and chromatin accessibility, respectively. SOURCE: Zhuqiang Zhang (zhangzhuqiang@ibp.ac.cn) - Institute of Biophysics, CAS