DPN muscle exhibits features of degeneration with attempted regeneration.  In the most severely pathological muscle samples, regeneration appears to be stymied and our data suggest that this may be partly due to intrinsic dysfunction of the satellite cell pool in addition to extrinsic structural pathology (e.g. nerve damage). SOURCE: Bo Zhang (zhangbo@wusm.wustl.edu) -  Washington University School of Medicine

Pluto Bioinformatics

GSE143979: Skeletal muscle regeneration is compromised in advanced diabetic peripheral neuropathy