Pluto Bioinformatics

GSE112642: Single cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta

Bulk RNA sequencing

We present single-cell mRNA-Sequencing of various endothelial and hematopoietic populations isolated from the mouse embryonic aorta at E10 and E11. Our study reveals the transcriptional dynamics occuring during endothelial to hematopoietic transition, the process responsible for the production of hematopoietic stem cells. SOURCE: Chloé Baron (c.baron@hubrecht.eu) - Hubrecht Institute