Pluto Bioinformatics

GSE61425: The miR-155/PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation [RNA-Seq]

Bulk RNA sequencing

miR-155 inhibits PU.1 expression, leading to the initiation of the initiation of plasma cell differentiation pathway. Additional PU.1 targets include a network of genes whose products are involved in adhesion, with direct links to B:T interactions. SOURCE: Simon,Richard,Andrews (simon.andrews@babraham.ac.uk) - Bioinformatics The Babraham Institute