Pluto Bioinformatics

GSE85193: A novel target of CD274 involvement in AML development

Bulk RNA sequencing

We report abonormally expressed genes of MLL-AF9 induced CD274-/- AML mice by RNA-seq analysis. Cyclin D2 was found down-regulated in CD274 depleted AML LSCs, suggesting it might be a novel target gene of CD274 involvement in AML advancement. SOURCE: Xianghua Yi (271337708@qq.com) - Tongji hospital