Pluto Bioinformatics

GSE141387: O-glycan initiation directs distinct biological pathways and controls epithelial differentiation

Bulk RNA sequencing

We used RNA_Seq to quantify cellular transcripts in human spontaneously immortalized HaCaT keratinocytes upon knock out of GALNT1, GALNT2, or GALNT3 - most abundantly expressed enzyme isoforms initiating mucin-type O-linked glycosylation. SOURCE: Hiren,J,Joshi (joshi@sund.ku.dk) - Copenhagen Center for Glycomics Copenhagen University