Pluto Bioinformatics

GSE112401: Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor and estrogen receptor signalling pathways in endocrine resistant breast cancer

Bulk RNA sequencing

Our data supports the potential combination of inhibition of ERBB2/3 signalling with mTORC1 perturbation and endocrine therapy in patients who have relapsed on endocrine therapy and retain a functional ER. SOURCE: Eugene Schuster (gschuster@icr.ac.uk) - Endocrinology Institute of Cancer Research