Pluto Bioinformatics

GSE139452: The effect of beta-glucan - induced trained immunity on the transcriptomic profile of bone marrow granulocyte-macrophage progenitors (GMP)

Bulk RNA sequencing

Induction of trained immunity by beta-glucan affects myeloid cells and their bone marrow progenitors. In particular, broad alterations in the transcriptome of trained myeloid cells have been demonstrated. In this study, we performed RNA sequencing in GMP from beta-glucan treated mice, as compared to control-treated mice, in order to investigate the impact of trained immunity on the transcriptomic profile of GMP. SOURCE: Triantafyllos Chavakis (Triantafyllos.Chavakis@uniklinikum-dresden.de) - Chavakis Lab Medizinische Fakultät der TU Dresden