Pluto Bioinformatics

GSE153079: cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Bulk RNA sequencing

A disturbance of histone protein composition renders nuclear DNA immunogenic, inducing a type I interferon response to self. SOURCE: Yanick Crow (yanick.crow@igmm.ed.ac.uk) - University of Edinburgh