Because niclosamide inhibits growth and progression of endometriotic lesions, we performed RNA-seq in order to identify genes whose expression is regulated by niclosamide in endometriotic lesions. Our results shown that niclosamide modulates several genes related to cell signaling, extracellular matrix, and inflammatory signaling. SOURCE: Kanako Hayashi (khayashi@siumed.edu) -  Southern Illinois University School of Medicine

Pluto Bioinformatics

GSE79698: The effect of niclosamide on the growth and progression of endometriosis in an experimental mouse model