Pluto Bioinformatics

GSE99409: Plagl1/Zac1 regulates extracellular matrix genes and the imprinted gene network

Bulk RNA sequencing

In order to determine the targets of the imprinted transcription factor Zac1, we compared wild type and Zac1-mutant MEFs and measured the differentially expressed genes by RNA-seq. Genes deregulated in the absence of Zac1 include genes belonging to the Imprinted Gene Network and genes coding for the extra-cellular matrix. SOURCE: Tristan Bouschet (tristan.bouschet@igf.cnrs.fr) - Functional Genomics of Imprinted Genes Institut de Génomique Fonctionnelle