Pluto Bioinformatics

GSE112365: A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis

Bulk RNA sequencing

Deficiency of deacetylase SIRT1 or its downstream target PRRX1 promotes breast cancer stemness and metastasis. To explore the mechnisms of SIRT1 and its downstream target PRRX1 in breast cancer, we analysed the gene expressions in breast cancer BT549 cells with SIRT1 knockout or PRRX1 knockout or not. SOURCE: Xiaolong Tang (terrytang15szu@163.com) - shenzhen university