Pluto Bioinformatics

GSE143909: Differential gene expression profile of S100A4 null mouse lens

Bulk RNA sequencing

Whole lens transcriptome profiling by RNA-seq analysis was performed to investigate the role of S100A4 in lens architecture and function. These studies yielded the intriguing discovery that absence of S100A4 in the lens results in robust induction of gene expression of S100A5, an olfactory sensory neuron specific protein, and of genes encoding various photoreceptor and Mller glial cell proteins SOURCE: Rupalatha Maddala Duke University