Pluto Bioinformatics

GSE63813: RNA sequencing of allelic series of miR-17~92 mutant embryos.

Bulk RNA sequencing

We report the generation of an allelic series of miR-17~92 mutant mice, each carrying the targeted deletion of specific miRNA families encoded by the cluster. We integrate the phenotypic characterization of these strains with RNA-seq analysis showing the consequences of selective miRNA inactivation on gene expression in the developing embryo. SOURCE: Andrea Ventura (venturaa@mskcc.org) - Ventura Memorial Sloan Kettering Cancer Center