Induction of trained immunity by beta-glucan has been shown to promote transcriptomic alterations in myeloid cells. Monocytes are involved in the immune responses against tumors. In this study, we performed RNA sequencing in tumor-infiltrated monocytes from mice in order to investigate the impact of trained immunity on the transcriptomic profile of monocytes in the tumor setting. SOURCE: Triantafyllos Chavakis (Triantafyllos.Chavakis@uniklinikum-dresden.de) - Chavakis Lab Medizinische Fakultät der TU Dresden

Pluto Bioinformatics

GSE139451: The effect of beta-glucan - induced trained immunity on the transcriptomic profile of tumor-associated monocytes