Pluto Bioinformatics

GSE123891: EOFAD-causing mutations in psen1 orchestrate dedifferentiation through remodeling of the chromatin landscape in hiPSC-derived neurons [RNA-Seq]

Bulk RNA sequencing

In this work, we used an integrative, multi-omics approach and systems-level analysis to generate a mechanistic disease model for EOFAD in an hiPSC-derived neuron model system. SOURCE: Shankar Subramaniam University of California, San Diego