Pluto Bioinformatics

GSE97696: Chemical Inhibition of Ezh2 Enhances Ex Vivo B cell Differentiation

Bulk RNA sequencing

To understand the role of Ezh2 in B cell differentiation B cells were stimulated ex vivo with LPS, Il2, and Il5 in the presence of DMSO or the selective Ezh2 inhibitor GSK343. Following 3 days culture, RNA-seq was performed to identify the molecular effects of Ezh2 inhibition on B cell differentiation. SOURCE: Chris Scharer ( - Jeremy Boss Emory University

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