Pluto Bioinformatics

GSE113817: Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells

Bulk RNA sequencing

Transcription factor Bach1 is a member of the alkaline leucine zipper protein family. Our results therefore highlight a critical role for Bach1 proteins in a regulatory network that integrates essential Wnt/-catenin and nodal-Smad signaling to repress mesendodermal differentiation of pluripotent cells SOURCE: Dan Meng (dmeng@fudan.edu.cn) - Dr Meng's Lab Fudan University